Netherlands scored 78 runs off 73 balls from their captain Scott Edwards to post 238 for 7 in 41 overs in the weather-affected match.
But Jason Roy made his 100th ODI with a scintillating 60-ball 73 while Phil Salt smashed a 54-ball 77 as England put the fight back to the Netherlands.
Roy was one of the few England batsmen who missed his world record 498/4 48 hours earlier, but in a contest of 41 overs per side, he hit top form to chase down 236 runs. England reached 239/4. Won the match easily in 36.1 overs.
Roy, who sent his first nine balls to the boundary, and Salt put on 139 for the opening wicket in 17 overs when Roy was dismissed. Although England quickly lost three more wickets to post 177/4 in the 26th over, David Malan and Moeen Ali stitched an unbeaten 62-run stand to help England win. Malan remained unbeaten on 36 while Moeen Ali remained unbeaten on 42.
Earlier, Scott Edwards handled the Netherlands innings with a brilliant half-century. Bass de Leide (34), Teja Nidamanuru (28) and Logan van Beek (30 not out) started for the Netherlands but could not contribute big enough as they finished with equal scores.
Brief scores: Netherlands 235/7 in 41 overs (Scott Edwards 78, Bass de Lead 34; David Willey 2/46, Adil Rashid 2/50) lost to England 239/4 in 36.1 overs (Jason Roy 73, Phil Salt 77, Moeen Ali 42 not out, Tom Cooper 1/25) by six wickets.
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