Covid: Paxlovid rebound can be contagious even without any symptoms, says study

White House physician Kevin O’Connor wrote in a memo that US President Joe Biden, who first tested positive for COVID-19 on July 21, received his negative test results earlier this week. In, one of the “rebound” cases has tested positive again. on Saturday.

Biden, 79, was fully vaccinated and boosted twice, and also took PaxLovid.

O’Connor wrote that the president “has not experienced a re-emergence of symptoms, and continues to feel quite well” but will resume strict isolation procedures.

One such case happened when White House Chief Medical Adviser Anthony S. Fauci tested positive last month.

The study, posted on the pre-print website, included 31 non-immunocompromised patients between the ages of 31 and SARS-CoV-2 viral symptoms after the Paxlovid tablet (nirmatrelavir and ritonavir tablets, co-packed for oral use). Load relief is described. up to 71 years.

Most patients improved rapidly after treatment with Paxlovid and had negative antigen or PCR tests before resumption at 9–12 days of illness.

Relapse symptoms were often described as cold symptoms, although some patients experienced fatigue and headache recurrence. All relapses resolved without additional antiviral treatment.

Viral load during relapse was comparable to levels during initial infection. Sequencing in three patients indicated that the relapse was not due to a treatment-emergent mutation or to infection with a different viral strain.

One symptomatic and one pre-symptomatic patient transmitted SARS-CoV-2 to family members during relapse.

“The presence of high viral loads and the occurrence of two transmission events suggest that patients should be isolated until the antigen test is negative,” the researchers write in the paper.

In clinical trials, Paxlovid has been shown to reduce the odds that a person at risk of severe covid will need hospitalization by about 90 percent, compared to placebo.

Meanwhile, the US Centers for Disease Control and Prevention last week issued new guidance for people experiencing a Covid rebound after PaxLovid, CNN reported.

The CDC said people who test positive again and whose symptoms come back after finishing their antiviral pills should resume their isolation period and isolate for a full five days.

The agency said people can end their isolation period after those five additional days as long as their fever has gone for 24 hours without fever-reducing medication and they are feeling better. The agency has also recommended people to wear masks for 10 days after their symptoms return, the report said.

Disclaimer: This story is auto-aggregated by a computer program and is not created or edited by FreshersLIVE.Publisher : IANS-media

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